Friday, April 26, 2013

Classic Note For iOS Is Bringing Blocky Back

Screen Shot 2013-04-25 at 5.33.44 PMIn case you can't wait for Jony Ive to give iOS a complete revamp, there's Classic Note, an app that will bring back a bit of the Woz-Jobs magic in fully 128K glory. The app includes a note taker and calculator into a package that harkens back to the days of the original Macintosh.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/NTdGjxruCNU/

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Social Media & Your Business | Florida Web Design Company - Atilus

I?ve been on a mission lately ? to educate businesses on what matters to their bottom line.

Do you feel you?re spending too much on conventional advertising (yellow pages, print magazines, etc.) and not seeing a return? Struggling to get to the next level? Sick of being a slave to the stop-start cycle all small businesses go through ? when it comes to sales and marketing?

I?ve heard in various circles that social media is the answer ? but you?re completely wrong.?

Let me explain.

It?s been my experience that you don?t really care about the Internet. It?s flashy, sexy, we all spend too much time distracting ourselves on it ? and very little of that time is productive (at least for me :) . However, when it comes to your business? Internet presence there?s a lot of information ? too much probably, and a lot of mis-information confusing everyone. You don?t want to worry about the web, you just need it to work for you ? or at least I?m trying to convince you it will.

There are some very simple concepts you must understand in order to grow your business like you never thought possible. You want to step your business up to the next level, and the Internet is a perfect place to do that. Just probably not in the way you think.

First,?understand?your business is your website.?

Most people think their business is a part of their advertising/marketing plan ? and to some extent I would have to agree. But, what we struggle to educate our potential clients and even current clients on is that as a whole ? it?s really not. It is your business. Your website, is akin to your brick-and-mortar storefront. It?s where customers go to learn more about your services, but generally, in-and-of-itself?YOUR WEBSITE IS NOT THE WAY YOUR BUSINESS GETS FOUND.

Your business gets found by the marketing/advertising plan you put in place, and all of the supplemental things you do on your website, and on the web ? to point people back to your website. This is everything, your content strategy (or search engine optimization), paid online advertising (through pay per click ads, or banner ads on appropriate websites), social media, etc.

And most of you would think social media is important.

Although I?d agree that it needs to be a part of the mix ? I would suggest it needs to be much lower on the totem poll of your business? marketing plan for a couple of reasons:

  • Generally Social Media is NOT How You Will Be Found By Your Customers
  • Social Media is Expensive (at least in time costs)

Instead I?d recommend the following mix for any business:?

  1. Website
  2. Email Newsletter
  3. Content Writing Strategy
  4. Pay Per Click Marketing
  5. Social Media -and/or- a mix of local review services

Website

This is the most important piece of the puzzle. Everything needs to point back to your website ? even those magazine ads. Now-a-days people are going through what Google calls the ?ZMOT? or zero moment of truth. It?s that stage where they hear about you, from friends, neighbors, or view an ad ? and immediately search for you online ? to learn more, read reviews, and investigate.

BECAUSE everything points back to your website, you must nurture it and treat it like a hub. Fill it with helpful information on your business, things your prospective customers need or want to know. Make sure it?s easy to navigate. And keep it up-to-date with timely articles that combine your area of expertise/industry with the concerns of your clientelle.

Email Newsletter

It?s old, it?s not flashy, and some of us are subscribed to far-too-many newsletters. But, hands-down enewsletters continue to be one of the best converting tools of any marketing mix. Here?s the best part ? your website copy (say articles on your blog) can help you fill that email newsletter, and in a best case-scenario you can even have a newsletter that gets taken care of AUTOMATICALLY when you post something new on your site.

This is old-school customer ?dripping? for the 21st century (although to be fair email newsletters were very popular in the 20th century).

Content Writing Strategy

Once the above 2 issues are addressed, working properly, and easy to navigate/signup for ? the next step is a content writing strategy. Set aside time each week, twice a day, or once a month (whatever it is stick to it) to continually update your website with helpful information. Each event a company representative attends, each update in your industry, is an opportunity for you to be heard and for potential clients and customers to find you.

This is vital because the previous step (email newsletters) and the additional steps I?m about to go through can not only be handled with this one step, but it also is vital to a search engine optimization strategy. I?ll spare you the boring details about why content is important from an SEO perspective (being seen on search engines) but the bottom line is - the more you get on your site ? the more you write ? the more you?ll be found.?

Pay Per Click Marketing

After ? and only after ? the above steps are complete it?s almost ALWAYS our recommendation to do pay per click marketing. You have the opportunity to get in front of your prospective customers at the exact moment they search for their problem ? of which your business provides a solution! Conversion rates for pay per click are amazing and costs are relatively low ? and the best part ? you ONLY PAY WHEN SOMEONE VISITS YOUR WEBSITE.

With the above considerations in mind (your website = your brick and mortar business) how much would you pay for qualified foot traffic into your business? Each and every person that walks in the door looking for exactly what you have to offer and ready to purchase?

There is no difference between this scenario on-or-off line ? except the Internet makes this shortening fo the sales-process possible.

Social Media

Finally, and only after the above are complete ? should social media be considered.

And here?s why ? social media means doing much of the above all over again (if you don?t have a great website in place or a content strategy). BUT if you do ? then setting these up ? and populating them with content is as simple as doing what you?re already doing. For example ? you can set up your website to auto fill in a tweet or facebook post EVERY TIME you write!

Also, Social Media is not generally how you?ll be found, it?s an extension to an old school newsletter ? which continues to provide a far higher return and far less time to manage ? for all of our clients that make it an active part of their marketing mix ? as opposed to social media.

To conclude, social media is important, but it?s not usually a vital part of the marketing mix for our clients and should only be considered after you?ve reviewed the above 4 pieces for your business.

?

Source: http://www.atilus.com/social-media-your-business/

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Thursday, April 25, 2013

Emma Stone Considering Lead Role In Woody Allen's Next Movie

Woody Allen is busy gathering together the cast for his next directorial effort, and it seems like Emma Stone could be his leading actor. Deadline is reporting that Stone is in talks to play the main role in Allen's latest. Little details are known about the movie beyond that it will shoot in the south [...]

Source: http://moviesblog.mtv.com/2013/04/24/emma-stone-woody-allen/

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Coyotes Kill Pet Dogs in Frontenac ? CBS St. Louis

FRONTENAC, Mo. (KMOX) - One Frontenac family says coyotes are to blame for the death of their two small dogs over the weekend.

Debbie Rudawsky says her sons let the two dogs out at about 10:15 at night, and when the dogs didn?t come back in after 20 minutes, the family became worried.

When the family decided to drive the neighborhood, looking for the dogs, they saw them in the yard, both had been attacked.

Debbie says the vet did an autopsy and concluded that each dog was attacked by a coyote.

?She felt very confident that it was at least two animals. The injuries were around the neck and the bruising was such that their necks were snapped.? said Rudawsky.

The Frontenac city administrator is sending a notice around to all resident to be on the watch for coyotes.

Do coyotes often roam the burbs?

Wildlife Biologist with the Missouri Department of Conservation, Tom Meister says coyotes are adaptable and have no natural predator so they can survive very well in the suburbs.

?They will eat just about anything? said Meister ?garbage, pet food, apples, so there is quite a smorgasbord for them in urban areas.?

Coyotes have, and will, invade neighborhoods, and right now they?ve likely had young and are out looking for food. ?What can you do? says Meister, ?harass them.? ?squirt them with a hose scare them by banging pots and pans.?

He also suggests keeping food out of sight and says make noise before you leave the house and don?t let your pets outside unattended.

Source: http://stlouis.cbslocal.com/2013/04/23/coyotes-kill-pet-dogs-in-frontenac/

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Israeli spy says Syria used chemical arms, U.S. unconvinced

By Maayan Lubell

JERUSALEM (Reuters) - Syrian government forces have used chemical weapons - probably nerve gas - in their fight against rebels trying to force out President Bashar al-Assad, the Israeli military's top intelligence analyst said on Tuesday.

The assessment met with skepticism from the United States, which has declared any use of chemical weapons in Syria's two-year-old civil war a "red line" that could trigger intervention.

U.S. Secretary of State John Kerry said he spoke to Israeli Prime Minister Benjamin Netanyahu and the latter "was not in a position to confirm" the briefing given by Itai Brun, a military intelligence brigadier-general, at a Tel Aviv conference.

"I don't know what the facts are," Kerry told reporters in Brussels.

Netanyahu's office declined comment on Kerry and Brun's remarks, made a day after U.S. Defense Secretary Chuck Hagel said while visiting Israel that Washington's spy agencies were still assessing whether such weapons had been employed.

"To the best of our understanding, there was use of lethal chemical weapons. Which chemical weapons? Probably sarin," Brun told Tel Aviv University's Institute for National Security Studies in the most definitive Israeli statement on the issue.

Forces loyal to Assad were behind the attacks on "armed (rebels) on a number of occasions in the past few months, including the most reported incident on March 19", Brun said.

The Syrian government and rebels last month accused each other of launching a chemical attack near the northern city of Aleppo.

Brun's comments were likely to deepen international concerns over events in Syria. Kerry said separately on Tuesday that NATO needed to consider how practically prepared it was to "respond to protect its members from a Syrian threat, including any potential chemical weapons threat".

FOAMING AT MOUTH

Speaking with a Powerpoint presentation showing what appeared to be a wounded or dead child, Brun said that foam coming out of victims' mouths and contracted pupils and "other signs" indicated deadly gas had been used.

Another Israeli military officer with knowledge of Brun's briefing said it drew on secret intelligence other than material available in the public domain.

"When an authority as senior as Brun makes such a statement in public, you can be sure it is based on solid evidence," the officer told Reuters on condition of anonymity.

Ralf Trapp, an independent consultant on chemical and biological weapons arms control based in Geneva, said the symptoms described by Israeli intelligence were "consistent with sarin gas," but photographic evidence alone was not conclusive.

Asked about Brun's remarks, Pentagon spokesman George Little signaled no change in the official U.S. line: "The United States continues to assess reports of chemical weapons use in Syria. The use of such weapons would be entirely unacceptable."

On Monday, Hagel said the use of chemical weapons by Assad's forces would be a "game changer" and the United States and Israel "have options for all contingencies".

Hagel met Netanyahu on Tuesday, a day after flying in an Israeli military helicopter over the occupied Golan Heights on the edge of the fighting in Syria.

"This is a difficult and dangerous time, this is a time when friends and allies must remain close, closer than ever," Hagel, in remarks to reporters before his talks with Netanyahu, said of the United States and Israel.

MIDDLE EAST TOUR

He travelled to Jordan, home to hundreds of thousands of Syrian refugees, for talks with Prince Faisal, King Abdullah's brother, and General Mashal al-Zaben, the country's military chief, and then on to Saudi Arabia for meetings with Crown Prince Salman bin Abdulaziz al Saud, the defense minister.

Discussions between Syria and the United Nations on a U.N. investigation of possible use of chemical weapons have been at an impasse due to the Syrian government's refusal to let the inspectors visit anywhere but Aleppo, diplomats and U.N. officials said last week.

U.N. diplomats said Britain and France had provided U.N. Secretary-General Ban Ki-moon's office with what they believed to be strong evidence that chemical weapons also had been used in the city of Homs.

Israel, which has advanced intelligence capabilities that it shares with its Western allies, has voiced concern that parts of Syria's chemical arsenal would end up in the hands of jihadi fighters or the Lebanese guerrilla group Hezbollah, with which it waged a war in 2006.

Israeli leaders have cautioned they will not allow that to happen. In an attack it has not formally confirmed, Israeli planes bombed an arms convoy in Syria in February, destroying anti-aircraft weapons destined for Hezbollah.

(Additional reporting by Jeffrey Heller and David Alexander in Riyadh, David Brunnstrom in Brussels and Anthony Deutsch in Amsterdam; Editing by Jeffrey Heller, Alison Williams and Mike Collett-White)

Source: http://news.yahoo.com/israeli-general-says-syria-government-forces-used-chemical-074330220.html

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HBT: Mets' Valdespin hits walk-off slam vs. Dodgers

Jordany Valdespin?s first homer of 2013 was memorable; he delivered a grand slam off Josh Wall in the bottom of the 10th to give the Mets a 7-3 win over the Dodgers on Wednesday.

It was the second walkoff slam of the year, with Baltimore?s Matt Wieters collecting the other.

Valdespin, who earlier entered the game as a pinch-hitter, got his chance to play hero after David Wright singled in Mike Baxter to tie the game in the bottom of the ninth. That gave Dodgers closer Brandon League his first blown save.

The homer was Valdespin?s ninth in 233 major league at-bats. He?s started just seven games for the Mets this season, as manager Terry Collins hasn?t quite figured out how best to use him yet. Valdespin, primarily a second baseman in the minors, opened the spring playing only the infield. However, during April, he?s made all of his starts in the outfield and has yet to play an inning in the infield.

For the Dodgers, it was a tough loss, yet it came with a couple of encouraging signs. Ted Lilly, who hadn?t pitched in the majors since shoulder surgery last May, held the Mets to one run over five innings in his 2013 debut. Also, the struggling Matt Kemp hit his first homer, a two-run shot off Matt Harvey. It was just the second homer surrendered by Harvey this season.

Source: http://hardballtalk.nbcsports.com/2013/04/25/mets-get-a-walkoff-grand-slam-to-beat-dodgers-in-10/related/

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Wednesday, April 10, 2013

EM ASIA FX-Won, Philippine peso top gainers as risk sentiment improves

* Weak Philippine exports data caps peso upside

* Won's upside limited on importers, N.Korea; missile eyed

* Ringgit cuts gains after 3-mth high with election date set

* S.Korea c.bank to cut rate on Thur; BI to hold rate

(Adds text, updates prices)

By Jongwoo Cheon

SINGAPORE, April 10 (Reuters) - The South Korean won and the

Philippine peso led emerging Asian currencies higher on

Wednesday as risk sentiment improved after strong China trade

data and a record Wall Street finish.

The Bank of Japan's bold easing programme also helped drive

up the Indonesian rupiah and the Malaysian ringgit

on views that investors will borrow a cheaper yen and

seek higher yields in Southeast Asia, traders said.

China's imports jumped 14.1 percent in March from a year

earlier, far exceeding expectations, indicating that domestic

demand in the world's second-largest economy was gathering steam

for a recovery.

"With risk appetite levels looking placid, markets may also

attempt to utilize any further indications of a global recovery

to channel into risk sensitive assets, especially if the FOMC

minutes tonight do not point to any urgency to tilt towards an

exit strategy," OCBC Bank said in a note.

The U.S. Federal Reserve is set to release the minutes of

the last monetary policy meeting and investors will look for

clues on whether the Fed would slow or halt its asset buying

stimulus.

In Asia, the central banks of South Korea and Indonesia are

scheduled to hold rate-setting meetings on Thursday. Bank of

Korea is expected to cut the interest rate, while Bank Indonesia

(BI) is seen leaving its benchmark rate unchanged, a pair of

Reuters poll showed.

PHILIPPINE PESO

The peso rose as interbank speculators covered short

positions, although data showing declining exports capped the

currency's upside, traders said.

Philippine exports fell for the second consecutive month in

February, posting the steepest drop in 14 months, casting doubt

on the government's first quarter growth forecast.

"It is more of temporary long dollar fix adjustment," said a

Philippine bank trader in Manila, referring to cutting bullish

dollar positions.

"But weak data may lead to an eventual weakening of the

peso," the trader said, adding the local currency is seen having

resistance around 41.10.

RUPIAH

The rupiah gained on bond inflows, although dollar demand

from corporates limited its gains, traders said.

BI was seen buying the rupiah from 9,710 per dollar, traders

added.

Investors are keeping an eye on whether BI tightens policy

by hiking the overnight deposit facility rate, called FASBI, to

help ease the country's current account deficit.

"BI should increase the FASBI rate this or next month,

although I think the next month is more possible," said a

Jakarta-based trader, adding the raise would support the rupiah.

WON

The won gained on demand from exporters' for settlements and

as local investors covered more short positions.

But its upside was capped by the geopolitical tension in the

peninsula and expectations of dollar demand linked to companies'

dividend payments to foreign shareholders.

South Korea said it has asked China, North Korea's only

major ally, to rein in the hermit state and has raised its

surveillance after the North moved at least one long-range

missile in readiness for a possible launch.

Local importers bought dollars for payments, traders said.

But some investors expected the won to rebound a bit more as

the currency is still seen excessively sold.

Seoul does not consider recent foreign capital outflows from

its markets to be a major cause for concern and that foreign

currency liquidity conditions remain stable, a senior finance

ministry official also said.

"The won is expected fall, probably to 1,145 per dollar, if

the North launches a missile, but it will quickly rebound.

Dollar long positions look still heavy," said a senior foreign

bank trader in Seoul.

The dollar/won's 14-day RSI stood at 70.4, still above the

70-threshold.

"I think the won saw a bottom, so it will be better to buy

the won whenever it falls," the trader added.

RINGGIT

The ringgit earlier hit 3.0180 to the U.S. dollar, its

strongest since Jan. 21, according to Thomson Reuters data, on

bond inflows and demand against the Singapore dollar.

The five-year government bond yield fell to 3.168

percent and the 10-year bond yield slid to 3.399

percent. Both were their lowest since late July last year.

But the Malaysian currency gave up most of earlier gains as

investors took profits after the country set May 5 as a date for

a general election.

Traders and analysts said the ringgit has priced a narrow

victory for the National Front led by Prime Minister Najib Razak

in. Opinion polls also suggest such a result.

CURRENCIES VS U.S. DOLLAR

Change on the day at 0645 GMT

Currency Latest bid Previous day Pct Move

Japan yen 99.09 99.04 -0.05

Sing dlr 1.2373 1.2395 +0.18

Taiwan dlr 29.982 30.050 +0.23

Korean won 1135.35 1139.40 +0.36

Baht 29.00 29.01 +0.03

Peso 41.13 41.27 +0.35

Rupiah 9695.00 9718.00 +0.24

Rupee 54.53 54.58 +0.10

Ringgit 3.0335 3.0370 +0.12

Yuan 6.1935 6.2024 +0.14

Change so far in 2013

Currency Latest bid End prev year Pct Move

Japan yen 99.09 86.79 -12.41

Sing dlr 1.2373 1.2219 -1.24

Taiwan dlr 29.982 29.136 -2.82

Korean won 1135.35 1070.60 -5.70

Baht 29.00 30.61 +5.55

Peso 41.13 41.05 -0.18

Rupiah 9695.00 9630.00 -0.67

Rupee 54.53 54.99 +0.85

Ringgit 3.0335 3.0580 +0.81

Yuan 6.1935 6.2303 +0.59

(Additional reporting by IFR Markets' Catherine Tan; Editing by

Sanjeev Miglani)

Source: http://news.yahoo.com/em-asia-fx-won-philippine-peso-top-gainers-074412266--finance.html

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Saturday, April 6, 2013

Clayton Christensen Talks Venture Capital, Crowd Funding, And How To Measure Your Life

IMG_2640Editor?s note:?Derek?Andersen?is the founder of?Startup Grind, a 40-city community bringing the global startup world together while educating, inspiring, and connecting entrepreneurs. There are few people whose impact on entrepreneurs and business in general you hear about as frequently as Clayton Christensen. Clay’s body of work includes co-founding a?publicly?traded company, being a Rhodes Scholar,?writing one of the most influential?business books?of our generation,?fighting cancer?and a stroke that forced him to relearn to speak, teaching thousands at the Harvard Business School, and raising five children. He has accomplished gigantic things, not to mention he stands 6 ’8″ and today is also his birthday so please wish?him?well. When I heard he would speak at Startup Grind 2013, excitement and then panic raced through my bald head. Luckily one of the very best in the business, Mark Suster of GRB Partners was gracious enough to come and represent the startup community at the interview. Mark has written?a great recap?of his conversation, but it seems appropriate to followup with this audience and share the entire interview from a few weeks ago. The Innovator’s Dilemma?as you might know outlines how companies with historically successful products and market share will be disrupted and beaten unless they are innovative again and again. Clayton also recently co-authored?How Will You Measure Your Life??which explains how like in business you need to plan in order to be successful in your personal life or you run the risk of failing your family and betraying your values. Read or watch the?fascinating?interview below. ———————– MARK:? Welcome to StartUp Grind!? I thought we would start with the disruption of education.? Because you?re a professor and I thought that would put me on more comfortable grounds. CLAYTON: Perfect. MARK:? We?ll come right back to venture capital, I promise.? What are your feelings about education in America ? the doubling over the last few years of consumer debt over education, and the fact that technology might just make what you do much more available at a lower cost for more people, which in itself matches I think your definition of disruption, and what?s going on with Udemy and Stanford and other places.? I?d love to hear that. CLAYTON:? Boy, it?s a great question.? I wrote my first piece about the disruption of the Harvard Business School in 1999.? Because you could see this coming.? I haven?t yet done the one about the disruption of the Stanford Business School.?

Source: http://feedproxy.google.com/~r/Techcrunch/~3/qaBImNFpoB8/

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Friday, April 5, 2013

2013 NFL draft: Mike Mayock ranks Eric Fisher over Luke Joeckel

Mike Mayock released his latest positional rankings and for the first time he's got Central Michigan's Eric Fisher ranked ahead of Texas A&M's Luke Joeckel as the top offensive tackle in the 2013 draft class.

"This is in now way an indictment of Luke Joeckel who I think will be an all pro 3 years from now," explained Mayock. "It's more an indication of my belief that there's a little more upside with Eric Fisher. He's longer, he's got better feet and he's a little bit more athletic."

"I went back and watched the Senior Bowl practices again and it confirmed my belief... At the end of the day they're both going to be all pros but I think Fisher's ceiling is a little bit higher."

Mayock said that this is a direction he's been heading for a few months now and that the tape helped his decision as long.

"The only little issue I had with Joeckel is that every tape I put on he got beat across his face 2 or 3 times every game. Against Florida, 3 times giving up a sack, against Alabama twice. Now they're quality opponents, but I just think Eric Fisher gives you the same downside but more upside."

While Mayock likes Fisher's upside, he said that the OT with the most upside in the entire draft is LT Lane Johnson. He believes that all 3 will go in the top 10.

When asked whether the rise of these OTs was mostly about their skill or the relative lack of other top end talent in the draft, Mayock said it was the former. He said all 3 are right now rated as good or better than Joe Thomas was coming out in 2007.

? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Source: http://www.bleedinggreennation.com/2013/4/5/4188200/2013-nfl-draft-mike-mayock-ranks-eric-fisher-over-luke-joeckel

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PFT: Mathieu meets with Bengals, Bucs; Pats next

KasaGetty Images

To little fanfare and no surprise, the NFL officially has closed the books on the investigation that was sparked by accounts of inappropriate questions being posed to incoming rookies (also known as ?job applicants?) at the Scouting Combine.

According to Mike Freeman of CBSSports.com, the NFL found no wrongdoing.

?Our review has not established any specific violations, but we have made it clear to our clubs what is acceptable when interviewing potential players and other job candidates,? a league spokesman told Freeman.

So is the NFL saying that Colorado tight end Nick Kasa wasn?t asked, ?Do you like girls??? No.? As Judy Battista of the New York Times reported two weeks ago, the NFL has concluded that this specific question wasn?t part of the job interview.? Even though it was asked during, you know, a job interview.

In no other industry would a question like this be unpunished.? But that?s largely because the NFL is one of the few industries in which a question like this will lead to no liability.

The NFL doesn?t hire players who walk in off the street and fill out an application and wait to get a call back from the manager.? Players who make it to the Scouting Combine already are products of the football machine.? They realize that, from time to time, things that otherwise would seem inappropriate will be said.

Besides, they just want to play football.? Filing a lawsuit against the NFL will tend to keep that from happening (unless they sue for concussions).? Football players always will choose the chance to play football over the hard-to-prove notion that someone else got a roster spot because the team believed the player who wasn?t chosen or who ultimately was cut is gay.

So with no outside accountability to fear, the NFL has no reason to transform a situation that easily can be swept under the rug into a story that stretches over multiple news cycles and that lingers longer than the scent of a woman whom a player may or may not like.

And who really cares if he does?

Source: http://profootballtalk.nbcsports.com/2013/04/04/tyrann-mathieu-visiting-buccaneers/related/

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New measurement of crocodilian nerves could help scientists understand ancient animals

Apr. 4, 2013 ? Crocodilians have nerves on their faces that are so sensitive, they can detect a change in a pond when a single drop hits the water surface several feet away. Alligators and crocodiles use these "invisible whiskers" to detect prey when hunting. Now, a new study from the University of Missouri has measured the nerves responsible for this function, which will help biologists understand how today's animals, as well as dinosaurs and crocodiles that lived millions of years ago, interact with the environment around them.

"The trigeminal nerve is the nerve responsible for detection of sensations of the face," said Casey Holliday, assistant professor of anatomy in the MU School of Medicine. "While we've known about these sensitive nerves in crocodiles, we've never measured the size of the nerve bundle, or ganglion, in their skulls, until now. When compared to humans, this trigeminal nerve in crocodiles is huge."

The key to this measurement is a specific hole in the skull. The trigeminal nerve is rooted inside the skull, but must travel through a large hole before it branches out to reach the crocodile's skin on its face. By examining how the skull size, brain size and ganglion size relate to each other, scientists can estimate how sensitive the face is. Eventually, Holliday hopes to measure this nerve in other ancient and contemporary species to learn more about animal behavior.

"Currently, we rely on alligators, crocodiles and birds to provide us with information about how ancient reptiles, such as pre-historic crocodiles and dinosaurs, functioned," said Holliday, who co-authored the study with doctoral student Ian George. "However, the first thing we have to do is to understand how the living animals function."

When comparing the size of the hole for the trigeminal nerve found in alligators to that of certain dinosaurs, George says that the hole in the much-larger dinosaur skull is very similar in size or even smaller, which could give scientists more information about how well dinosaurs could detect small sensations on the face. From there, the scientists can start to trace the evolution of this nerve and the mechanism used by crocodiles.

"Some species of ancient crocodiles lived on land and they probably wouldn't have a use for a sensitive face that can detect disturbances in the water," George said. "So our next step is to trace back and determine when the nerve got bigger and see how that might have paralleled the animals' ecology."

Holliday says that this information will aid future research, including when his team will examine skulls of ancient crocodiles. Understanding this nerve and its functions could also lead to better understanding of the anatomical basis for behavior in many living animals, including fish, electric eels, platypi and humans.

"The same way that we would look at the size of the visual cortex in the brain to understand how well an animal might see, we can now look at the trigeminal nerve in animals to determine how sensitive their skin on their faces is," Holliday said.

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Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ian D. George, Casey M. Holliday. Trigeminal Nerve Morphology in Alligator mississippiensis and Its Significance for Crocodyliform Facial Sensation and Evolution. The Anatomical Record, 13 FEB 2013 DOI: 10.1002/ar.22666

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/678x3GJOG1g/130404152623.htm

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Thursday, April 4, 2013

Gingrich: Gay-marriage will divide the GOP

Former House Speaker Newt Gingrich (Chip Somodevilla/Getty Images)

As more Americans and lawmakers accept same-sex marriage, the Republican Party increasingly will be divided over the issue, former House Speaker Newt Gingrich said on Thursday.

"The Republican Party is going to be torn on this issue. The bulk of the party is going to be very resistant and is very supportive of traditional marriage, and parts of the party are going to flake off. Parties do that," Gingrich told a group of reporters at a breakfast meeting at National Review magazine's Washington, D.C., office. "The country is gradually evolving. The country is thinking this thing through. It creates complexities."

Gingrich made clear that he still believes civil marriage should be exclusively between one man and one woman, but he appeared open to the possibility that the definition could change in the future.

But the bigger issue, he said, concerned the future of religious liberty, which could be at risk if the nation changes its marriage laws.

"Those of us who are concerned about religious liberty have to figure out how we fight to ensure that you don't get this kind of tyranny of secularism, which I think is a very grave danger," Gingrich said, a reference to the possibility that churches that oppose same-sex marriage may be forced to conduct same-sex marriage ceremonies.

He also pointed to the recent decision by Health and Human Services to require religiously affiliated charities and organizations to provide health insurance that covers procedures that conflict with their faith's teachings. "I'm actually intrigued, as an historian, for how long this cycle will last, because if you look at the long history of Christianity and the long history of traditional religions, you know, things come and go. Overall, betting on the historic survival of the Bible has been a reasonably good bet now for several thousand years."

Although there has not been a tidal shift in the Republican Party over the issue, several key Republicans have recently announced their support for same-sex marriage. This year, two GOP senators, Ohio's Rob Portman and Illinois' Mark Kirk, reversed their long-held stances on the issue. On the other side of the aisle, all but seven Democratic senators have said they support the unions.

Last week the Supreme Court heard two cases concerning same-sex marriage: one that examined the constitutionality of a voter-approved ban in California and another over the federal Defense of Marriage Act, which restricts the federal government from recognizing same-sex marriages conducted in states where it's legal. Gingrich predicted that the court would probably not make a sweeping ruling on either.

"If the court is wise, they will in fact take a very limited role and let this work itself out politically," Gingrich said. "This fight will keep evolving and, I think, become very different another day."

As for whether he plans to one day pursue the presidency again?he lost his bid for the Republican presidential nomination last year?Gingrich said he's leaving the possibility open. Whether or not he runs, Gingrich said he hopes to continue to play a role in mapping out the future of the party in his own way.

?I don?t rule it out, but we?re not spending any energy on" running, he said. "My instinct is that there will be a new generation of ideas and a new generation of candidates. That's my instinct. But, you know, I would like to be somebody who plays a role in developing a new generation of ideas."

Source: http://news.yahoo.com/blogs/ticket/newt-gingrich-gop-torn-over-same-sex-marriage-184751451--election.html

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What Are Some Of The FL Studio Packs?

For someone who is totally in league with the latest music world, understanding the term 'fl studio packs' is very easy. But for common people with no knowledge of the latest and the best and the current music trends, it may sound unfamiliar. Generally speaking sound packs or studio packs are modern beats of hip hop that are composed for creating hip hop instrumentals especially for the rap artists. The demand for such fl studio packs have been increasing since past few years and now you can see many beat makers putting their hip hop sound packs for sale to attract the aspiring producers.

Understanding studio packs

Some of the common inclusions of these sound packs are snares, percussion, custom drums, synth sounds and other effects blended together in combination. So, as to try out these packs for your own use, you need to understand this software well. Apart from being useful for making music, these sound packs for fl studio also contribute in other types of audio productions. A person using software such as Acid Loops, Fl Studio or Reason makes use of the drum kits and the samples provided by the sound pack.

Latest studio packs

There are many sound packs for fl studio currently available in the market-both offline and online. Some of the most popular are:


Raw keyboard Synth's collection

This sound pack is collection made up of 235 hot synth sounds that are suitable for the popular Fruity Loops program and can also be used for any type of sound format that says WAV. The collection has already become very popular amongst the youngsters and provides you with novel sound selection options. This gives you more scope for working with musical soundscapes. The pack is available directly for downloading through the site or you can also ask for the CD-ROM to be directly shipped to your doorsteps.

SampleSonic Sound effects

These sound packs provide you the effect equal to the quality of Hollywood. You can use the effects in this pack as interludes, intros and for skit productions. This pack includes phone rings, party background noise, car starts, 911 calls, thunderstorms, water running special effects, baby sounds, toilets flushing, sexy girls,
animal sounds and more.

There are a large variety of studio packs available both on the online store as well as the offline shops. All you have to do is explore a bit to get what suits you
the best.

Source: http://www.artipot.com/articles/1548086/what-are-some-of-the-fl-studio-packs.htm

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Hello, Facebook phone? Social network's 'new Home on Android' revealed

"Today we're finally gonna talk about that Facebook phone," said Mark Zuckerberg, Facebook CEO, as he took the stage at his headquarters in Menlo Park, Calif., to reveal Facebook Home, a new launcher that the social network will offer for Android phones.

The service ? available for download April 12 from Google Play ? is a launcher that works with apps that are already in your phone.

Tap your face and you can get options to go to the app menu, or straight to a messaging app, or to Facebook. The app launcher is customized, but includes apps that you got from Google Play (or sideloaded). These are not Facebook apps, like the games you'd play on the Facebook website.

"Cover feed" lets you scroll through updates, with huge, upright-oriented photos. If a post has comments, you can tap to see all of the comments, and respond to comments inline. There is also a notification pane, with SMS, messages and the most important posts appearing there.

"Chat heads" is a persistent messaging widget that appears in other apps. Facebook demonstrated a chat head over a New York Times app, and showed how a whole conversation can happen without leaving the app.

Some Android phones will have access to the free software, but HTC and AT&T will release the first phone with Home pre-installed, appropriately named the HTC First. It will go on sale April 12, and is available for preorder now from AT&T.

In the coming months, Home will also work on the HTC One X, HTC One X+, Samsung Galaxy S III and Samsung Galaxy Note II, as well as on the forthcoming HTC One and Samsung Galaxy S4 as well as on more devices.

Why didn't Facebook opt to build its own phone? "A great phone might sell 10 or 20 million units at best, but our community has over 1 billion people. Even if we built a really good phone, we'd only be serving 1 percent" of Facebook users, said Zuckerberg.

So Facebook is aiming at the home screen of every Android phone. "It sets the tone for your whole experience," he said.

"They have tried this before with little success," analyst Jeff Kagan said, pointing to previous smartphones with physical Facebook buttons.

Don't expect to see Facebook Home for Apple's iOS. Unlike Google, Apple does not allow launcher apps like Facebook Home.

With Home, Facebook is after the 750 million Android devices out there (actually, that number was released in March, odds are that there are significantly more activated Android devices at this point).

As long as the device has access to the Google Play store, it'll have the opportunity to become a "Facebook Phone."

And that's the catch: With so much functionality, will Facebook Home fly in the face of Google, by taking over the aspects of Android that Google ? the mobile operating system's lord protector ? tends to control?

"The reaction from Google will be interesting to see," mobile industry consultant Chetan Sharma told NBC News. "There's obviously overlap ... It seems to Google that it's underpinning their Google+ efforts. Longer term, I don't see them letting it go and letting other people do their work."

Additionally, Facebook doesn't just give Google+ a swift kick ? the social giant's gotta make some money, so odds are that it won't stop its invasion of Android with just the Facebook Home launcher.

Messaging, video chat, photos, these are services that Google may begrudgingly share with Facebook, because other software available in the Google Play store offers similar functionality.

But what happens when Facebook tries to push its own monetized apps ? Zynga games, for instance ? through the Facebook interface? That could prove to be the ultimate showdown with Google.

"Google takes their commitment to openness on Android seriously," Zuckerberg told reporters.

"Their operating system is designed from the ground up to support these things. It is theoretically possible that they will go back on [keeping it open], but I don't think this will happen. ? It would have to be a 180 (degree turn) on their philosophy."

You can view the entire Facebook Home presentation keynote here.

A demonstration of Facebook chat heads:

Facebook Home on the new HTC First:

Want more tech news or interesting links? You'll get plenty of both if you keep up with Rosa Golijan, the writer of this post, by following her on Twitter, subscribing to her Facebook posts, or circling her on Google+.

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Phone records probed after killing of Texas prosecutor and his wife

By Alastair Jamieson and Eric McClam, NBC News

Phone records for two mobile numbers were being examined Monday as investigators probing the killing of a Texas prosecutor and his wife sought possible links to the January slaying of another area district attorney and amid suggestions that a white supremacist was involved.

Authorities are looking at records for the two mobile numbers between Jan. 1 and Sunday, according to details of a search warrant, made public Monday and reported by NBCDFW.com. No more details were given in the warrant.

Kaufman County District Attorney Mike McLelland and his wife, Cynthia, were gunned down at their home outside Dallas on Saturday. The county?s Assistant District Attorney Mark Hasse was shot dead near the county courthouse on his way to work on Jan. 31.

The search warrant also revealed that the McLellands? bodies were initially found by a family friend who went to the residence after trying to contact the couple several times without success.

District Attorney Mike McLelland and his wife Cynthia were found shot to death in their home Saturday, just two months after the county's assistant DA, Mark Hasse, was gunned down outside the courthouse. NBC's Gabe Gutierrez reports.

The slayings have dismayed residents in the county, particularly in its main town, Kaufman.

"People are in absolute shock here," Joe Gibson, 21, the manager at Moon's Fried Chicken Cafeteria told Reuters.

Insurance agent Bobby Aga, 68, told Reuters: ?We have a strong tradition of law enforcement in this area. The criminal justice system here is something you don't mess with. It's the fabric of our community."

Authorities have not said the killings are linked and have not announced any leads in the McLellands? deaths ? although a county judge, Bruce Wood,?said Monday that "there has to be some connection."

Several people who are familiar with the case downplayed any possible connection to white supremacist prison gang, the Aryan Brotherhood of Texas, NBCDFW.com reported. Investigators say they have found nothing to indicate the Aryan Brotherhood was involved.

However, Rep. Ted Poe, a Republican and former Texas prosecutor, told CNN on Monday that he suspected the gang was involved, without saying where he was getting his information.

On the day Hasse was killed, the Kaufman County DA?s office was named among the investigative bodies involved in a racketeering case against the gang.

The hate group was suspected of ?actively planning retaliation? against police and prosecutors who helped gain indictments in Houston against dozens of its members,?the Dallas Morning News reported in February.

The Aryan Brotherhood has been in the state's prison system since the 1980s, when it began as a white supremacist gang that protected its members and ran illegal activities, including drug distribution, Terry Pelz, a former Texas prison warden and expert on the gang, told the Associated Press.

Four top leaders of the group were indicted in October for crimes ranging from murder to drug trafficking. Two months later, authorities issued the bulletin warning that the gang might try to retaliate against law enforcement for the investigation that also led to the arrest of 30 other members.

Hasse's death on Jan. 31 came the same day as the first guilty pleas were entered in the indictment, the AP reported.

Killing law enforcement representatives would be uncharacteristic of the group, Pelz said.

"They don't go around killing officials," he said. "They don't draw heat upon themselves."

Late Monday, Kaufman County Sheriff's office announced that Brandi Fernandez, First Assistant District Attorney, will fill the position of interim DA for a period of 21 days.

The murders serve as a reminder that officers of courts across the nation continually face threats, although these are rarely carried out.

Reuters and The Associated Press contributed to this report.

Related:

Texas community in 'shock' over slaying of DA, wife

District attorney, wife shot to death in Texas county where assistant DA was killed

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This story was originally published on

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Wednesday, April 3, 2013

Taken under the 'wing' of the small magellanic cloud: First detection of X-ray emission from young stars with masses similar to our Sun outside our Milky Way galaxy

Apr. 3, 2013 ? The Small Magellanic Cloud (SMC) is one of the Milky Way's closest galactic neighbors. Even though it is a small, or so-called dwarf galaxy, the SMC is so bright that it is visible to the unaided eye from the Southern Hemisphere and near the equator. Many navigators, including Ferdinand Magellan who lends his name to the SMC, used it to help find their way across the oceans.

Modern astronomers are also interested in studying the SMC (and its cousin, the Large Magellanic Cloud), but for very different reasons. Because the SMC is so close and bright, it offers an opportunity to study phenomena that are difficult to examine in more distant galaxies.

New Chandra data of the SMC have provided one such discovery: the first detection of X-ray emission from young stars with masses similar to our Sun outside our Milky Way galaxy. The new Chandra observations of these low-mass stars were made of the region known as the "Wing" of the SMC. In this composite image of the Wing the Chandra data is shown in purple, optical data from the Hubble Space Telescope is shown in red, green and blue and infrared data from the Spitzer Space Telescope is shown in red.

Astronomers call all elements heavier than hydrogen and helium -- that is, with more than two protons in the atom's nucleus -- "metals." The Wing is a region known to have fewer metals compared to most areas within the Milky Way. There are also relatively lower amounts of gas, dust, and stars in the Wing compared to the Milky Way.

Taken together, these properties make the Wing an excellent location to study the life cycle of stars and the gas lying in between them. Not only are these conditions typical for dwarf irregular galaxies like the SMC, they also mimic ones that would have existed in the early Universe.

Most star formation near the tip of the Wing is occurring in a small region known as NGC 602, which contains a collection of at least three star clusters. One of them, NGC 602a, is similar in age, mass, and size to the famous Orion Nebula Cluster. Researchers have studied NGC 602a to see if young stars -- that is, those only a few million years old -- have different properties when they have low levels of metals, like the ones found in NGC 602a.

Using Chandra, astronomers discovered extended X-ray emission, from the two most densely populated regions in NGC 602a. The extended X-ray cloud likely comes from the population of young, low-mass stars in the cluster, which have previously been picked out by infrared and optical surveys, using Spitzer and Hubble respectively. This emission is not likely to be hot gas blown away by massive stars, because the low metal content of stars in NGC 602a implies that these stars should have weak winds. The failure to detect X-ray emission from the most massive star in NGC 602a supports this conclusion, because X-ray emission is an indicator of the strength of winds from massive stars. No individual low-mass stars are detected, but the overlapping emission from several thousand stars is bright enough to be observed.

The Chandra results imply that the young, metal-poor stars in NGC 602a produce X-rays in a manner similar to stars with much higher metal content found in the Orion cluster in our galaxy. The authors speculate that if the X-ray properties of young stars are similar in different environments, then other related properties -- including the formation and evolution of disks where planets form -- are also likely to be similar.

X-ray emission traces the magnetic activity of young stars and is related to how efficiently their magnetic dynamo operates. Magnetic dynamos generate magnetic fields in stars through a process involving the star's speed of rotation, and convection, the rising and falling of hot gas in the star's interior.

The combined X-ray, optical and infrared data also revealed, for the first time outside our Galaxy, objects representative of an even younger stage of evolution of a star. These so-called ???young stellar objects??? have ages of a few thousand years and are still embedded in the pillar of dust and gas from which stars form, as in the famous "Pillars of Creation" of the Eagle Nebula.

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Story Source:

The above story is reprinted from materials provided by Chandra X-ray Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. L. M. Oskinova, W. Sun, C. J. Evans, V. H?nault-Brunet, Y.-H. Chu, J. S. Gallagher III, M. A. Guerrero, R. A. Gruendl, M. G?del, S. Silich, Y. Chen, Y. Naz?, R. Hainich, J. Reyes-Iturbide. Discovery of X-ray emission from young suns in the Small Magellanic Cloud. The Astrophysical Journal, 2013 [link]

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/kwRgKeQbMRI/130403104250.htm

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Learn Many Considerations When Buying Barbour Products online ...

barbour in considered the clothes brand that?s famous within the whole world. This company is about a wide selection of garments for guys, ladies, young people and kids. It is actually recognized as a general clothes company for the whole family members. This has been within the market for numerous years. This unique truth has enabled the company must always recognise different styles of customers. Along with getting in the marketplace for many years has allowed this type of brand to acquire trusted market share and also a attractive image. There are many reasons which have been associated with high demand for these particular items. These include availability of a wide variety of goods, outstanding quality, availability and competitive rates and others. These kinds of features happen to have been developed as a result of regular changes in quality and designs. Frequent testimonials conducted by third party institutions assist the producer to be aware of genuine preferences and expectation of already present shoppers. Therefore, unique wants of consumers are taken care of and completely happy. Just as pointed out much earlier, the company is about all attire products. Included in this are outdoor jackets for men, sweaters, blazers, shirts and handbags amongst others. All clothes are readily available for every family member. When ever one is doing searching for his loved ones, the individual does not have to jump from a single store to another location. Particular Barbour outlet stores delivers all garments she may need therefore saving time and energy. This gives a relevant area for discounts since one will buy in great quantity.

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Stillbirth or pre-term birth outcomes linked to elevated risk of blood clots after pregnancy

Stillbirth or pre-term birth outcomes linked to elevated risk of blood clots after pregnancy [ Back to EurekAlert! ] Public release date: 2-Apr-2013
[ | E-mail | Share Share ]

Contact: Andrea Slesinski
aslesinski@hematology.org
American Society of Hematology

(Washington)- Newly identified pregnancy-related events, such as stillbirth or pre-term birth, may dramatically increase a woman's risk of developing a potentially deadly blood clot immediately after pregnancy, according to the results of a large, population-based study published online today in Blood, the Journal of the American Society of Hematology (ASH).

Venous thromboembolism, or VTE, is a clotting disorder that includes both deep-vein thrombosis (DVT) and pulmonary embolism (PE). DVT is a blood clot that typically forms in the deep veins of the leg. It can develop into PE, a life-threatening condition that occurs when the clot breaks free and becomes lodged in the arteries of the lung, blocking blood flow. VTE is a rare but serious complication in pregnancy, and remains one of the leading causes of pregnancy-related death in many parts of the world. One preventive measure for VTE includes a daily dose of the blood thinner heparin. However, because heparin may not be cost effective or safe, current U.K. obstetric VTE risk guidelines suggest administering the drug only to women considered to be at high risk based on specific sets of risk factors which may not fully capture the true "at risk" population.

"Preventing VTE in pregnancy remains a challenging topic for clinicians since there is still disagreement as to which clinical, lifestyle, and socio-demographic factors qualify women as high-risk, and data are lacking about the relative impact of those factors on their risk of VTE," said author Matthew Grainge, PhD, of the Division of Epidemiology and Public Health at the University of Nottingham in the U.K. "Moreover, many studies have made the incorrect assumption that any risk factors identified have a similar impact on VTE rates in both pregnant women and new moms."

To understand the relative risk of VTE in women in the period between conception and birth (antepartum) and for up to 12 weeks after birth (postpartum) with the goal of optimizing the preventive use of heparin in this population, Dr. Grainge and colleagues designed a study examining data from more than 375,000 pregnancies in women ages 15-44 between January 1995 and July 2009. Data analysis was conducted through a retrospective review of The Health Improvement Network (THIN), a large primary-care database with input from more than 1,500 general practitioners across the U.K. Of the 375,000 pregnancies documented, the overall incidence of VTE was low, but higher during the postpartum period (338 per 100,000 person-years, which represents an individual's risk of an event during a one-year period) than during the pregnancy (84 per 100,000 person-years).

During the antepartum period, Dr. Grainge and colleagues found that the risk of VTE was highest in women who had reported inflammatory bowel disease (incidence rate ratio compared to women without the risk factor, or IRR, of 3.5) or pre-existing diabetes (IRR 3.1).

In the postpartum period, the team discovered a significant correlation between VTE risk and stillbirth (a six-fold increased risk of VTE compared with women who did not have a stillbirth, IRR 6.2), a risk factor that is not currently addressed in VTE risk assessment guidelines. Importantly, obese women with a high body mass index (BMI) of 30 or above also had a significantly increased VTE risk (IRR 3.75). The team also determined other factors that led to an increased risk of VTE, including a caesarian section delivery ( IRR 1.99), three or more previous births (IRR 2.07), pre-term birth (prior to 37 weeks gestation, IRR 2.69), and obstetric hemorrhage (IRR 2.89).

"The higher overall risks in the postpartum period may be attributable to a number of pregnancy-related factors, including delivery-related trauma, sudden increases in cardiac output and blood flow during delivery, and the thickening of the blood that occurs during late pregnancy, all of which may trigger a greater risk of clotting immediately following delivery," said Dr. Grainge.

According to the team's findings, other factors currently included in U.K. risk guidelines, such as smoking status, maternal age (over 35 years), and current systemic infection were only moderately associated with VTE in both antepartum and postpartum periods.

"Our results provide valuable information to help clinicians identify high-risk pregnant women and new mothers who may require some form of intervention to prevent future clots. The findings support the use of heparin to prevent blood clots in the postpartum period, when the actual risk of VTE is highest, clear risk factors have been identified, and duration of care would likely be limited to a few weeks (as compared to treating throughout the pregnancy)," added Dr. Grainge.

###

The study was carried out as part of a PhD project on VTE prevention in pregnancy being undertaken by Alyshah Abdul Sultan in collaboration with Professor Catherine Nelson-Piercy at the Women's Health Academic Centre at Guy's and St Thomas' Foundation Trust.

Blood, the most cited peer-reviewed publication in the field of hematology, is available weekly in print and online. Blood is the official journal of the American Society of Hematology (ASH), the world's largest professional society concerned with the causes and treatment of blood disorders.

ASH's mission is to further the understanding, diagnosis, treatment, and prevention of disorders affecting blood, bone marrow, and the immunologic, hemostatic, and vascular systems by promoting research, clinical care, education, training, and advocacy in hematology.

blood is a registered trademark of the American Society of Hematology.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Stillbirth or pre-term birth outcomes linked to elevated risk of blood clots after pregnancy [ Back to EurekAlert! ] Public release date: 2-Apr-2013
[ | E-mail | Share Share ]

Contact: Andrea Slesinski
aslesinski@hematology.org
American Society of Hematology

(Washington)- Newly identified pregnancy-related events, such as stillbirth or pre-term birth, may dramatically increase a woman's risk of developing a potentially deadly blood clot immediately after pregnancy, according to the results of a large, population-based study published online today in Blood, the Journal of the American Society of Hematology (ASH).

Venous thromboembolism, or VTE, is a clotting disorder that includes both deep-vein thrombosis (DVT) and pulmonary embolism (PE). DVT is a blood clot that typically forms in the deep veins of the leg. It can develop into PE, a life-threatening condition that occurs when the clot breaks free and becomes lodged in the arteries of the lung, blocking blood flow. VTE is a rare but serious complication in pregnancy, and remains one of the leading causes of pregnancy-related death in many parts of the world. One preventive measure for VTE includes a daily dose of the blood thinner heparin. However, because heparin may not be cost effective or safe, current U.K. obstetric VTE risk guidelines suggest administering the drug only to women considered to be at high risk based on specific sets of risk factors which may not fully capture the true "at risk" population.

"Preventing VTE in pregnancy remains a challenging topic for clinicians since there is still disagreement as to which clinical, lifestyle, and socio-demographic factors qualify women as high-risk, and data are lacking about the relative impact of those factors on their risk of VTE," said author Matthew Grainge, PhD, of the Division of Epidemiology and Public Health at the University of Nottingham in the U.K. "Moreover, many studies have made the incorrect assumption that any risk factors identified have a similar impact on VTE rates in both pregnant women and new moms."

To understand the relative risk of VTE in women in the period between conception and birth (antepartum) and for up to 12 weeks after birth (postpartum) with the goal of optimizing the preventive use of heparin in this population, Dr. Grainge and colleagues designed a study examining data from more than 375,000 pregnancies in women ages 15-44 between January 1995 and July 2009. Data analysis was conducted through a retrospective review of The Health Improvement Network (THIN), a large primary-care database with input from more than 1,500 general practitioners across the U.K. Of the 375,000 pregnancies documented, the overall incidence of VTE was low, but higher during the postpartum period (338 per 100,000 person-years, which represents an individual's risk of an event during a one-year period) than during the pregnancy (84 per 100,000 person-years).

During the antepartum period, Dr. Grainge and colleagues found that the risk of VTE was highest in women who had reported inflammatory bowel disease (incidence rate ratio compared to women without the risk factor, or IRR, of 3.5) or pre-existing diabetes (IRR 3.1).

In the postpartum period, the team discovered a significant correlation between VTE risk and stillbirth (a six-fold increased risk of VTE compared with women who did not have a stillbirth, IRR 6.2), a risk factor that is not currently addressed in VTE risk assessment guidelines. Importantly, obese women with a high body mass index (BMI) of 30 or above also had a significantly increased VTE risk (IRR 3.75). The team also determined other factors that led to an increased risk of VTE, including a caesarian section delivery ( IRR 1.99), three or more previous births (IRR 2.07), pre-term birth (prior to 37 weeks gestation, IRR 2.69), and obstetric hemorrhage (IRR 2.89).

"The higher overall risks in the postpartum period may be attributable to a number of pregnancy-related factors, including delivery-related trauma, sudden increases in cardiac output and blood flow during delivery, and the thickening of the blood that occurs during late pregnancy, all of which may trigger a greater risk of clotting immediately following delivery," said Dr. Grainge.

According to the team's findings, other factors currently included in U.K. risk guidelines, such as smoking status, maternal age (over 35 years), and current systemic infection were only moderately associated with VTE in both antepartum and postpartum periods.

"Our results provide valuable information to help clinicians identify high-risk pregnant women and new mothers who may require some form of intervention to prevent future clots. The findings support the use of heparin to prevent blood clots in the postpartum period, when the actual risk of VTE is highest, clear risk factors have been identified, and duration of care would likely be limited to a few weeks (as compared to treating throughout the pregnancy)," added Dr. Grainge.

###

The study was carried out as part of a PhD project on VTE prevention in pregnancy being undertaken by Alyshah Abdul Sultan in collaboration with Professor Catherine Nelson-Piercy at the Women's Health Academic Centre at Guy's and St Thomas' Foundation Trust.

Blood, the most cited peer-reviewed publication in the field of hematology, is available weekly in print and online. Blood is the official journal of the American Society of Hematology (ASH), the world's largest professional society concerned with the causes and treatment of blood disorders.

ASH's mission is to further the understanding, diagnosis, treatment, and prevention of disorders affecting blood, bone marrow, and the immunologic, hemostatic, and vascular systems by promoting research, clinical care, education, training, and advocacy in hematology.

blood is a registered trademark of the American Society of Hematology.


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Source: http://www.eurekalert.org/pub_releases/2013-04/asoh-sop040213.php

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Tuesday, April 2, 2013

How Much Do You Care About Your Online Privacy?

How Much Do You Care About Your Online Privacy?We talk a lot about online privacy here, but sometimes we'll sacrifice that privacy in order to get a good deal. So, we want to know, how much do you care about online privacy?

In a recent New York Times article they dig into how willing we are to give over our data if we have something to gain from it (like a shopping deal), or when we're just too distracted to care. In the end, most of us reveal private information without really noticing we do it. Of course, we know why we should care about online privacy, but we want to hear it: how much do you actually care about your online privacy?

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/Alc35YvHFQE/how-much-do-you-care-about-your-online-privacy

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HTC One also coming to Sprint from April 19

HTC One

$199.99 with 32GB of storage, pre-orders start April 5

Following on from AT&T's announcement earlier today, rival network Sprint has announced that it too will start selling the HTC One from Apr. 19. Pre-orders on Sprint begin a day later than AT&T this Friday, April 5. Sprint will sell the phone with 32GB of storage for $199.99 on a two-year plan.

Doesn't look like Sprint's offering any free accessories with preorders, unofortunately.

Like AT&T, Sprint will carry the phone in silver and black color options.



Source: http://feedproxy.google.com/~r/androidcentral/~3/4GTcuRKhz6w/story01.htm

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